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What Is CBD Bioavailability, And Why Does It Matter?

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Summary:

In general, not all of the CBD you consume will directly affect your body, only a certain percentage will be able to enter your systemic circulation and produce its active effects. This percentage is bioavailability, and a desire to maximize the CBD bioavailability may impact your choice of CBD products.

In this article, we discuss bioavailability, CBD bioavailability, maximizing CBD bioavailability, CBD vape bioavailability, and “water-soluble” CBD bioavailability.

What Is CBD Bioavailability, And Why Does It Matter?

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Scientist and Microscope

Any time you consume a drug or other substance only a limited amount will actually make it into your systemic circulation. A desire to maximize the CBD absorbed by your system may impact your choice of CBD products.

In general, not all of the CBD you consume will directly affect your body: only a certain percentage will be able to enter your systemic circulation and produce its active effects. This percentage is referred to in science as “bioavailability,” and it strongly depends on the manner in which CBD is introduced to your system. For example, the oral bioavailability of CBD is roughly 15 percent. That means for every 100 milligrams of CBD that you eat, only 15 milligrams will actually reach your bloodstream.

‘Should I Be Vaping CBD?’: Why Vaporization Works Better Than Ingestion

Bioavailability

In pharmacology, bioavailability is a subcategory of absorption.

Bioavailability refers to the extent and rate at which the active moiety (drug or metabolite) enters systemic circulation, thereby accessing the site of action.

Bioavailability of a drug is largely determined by the properties of the dosage form, which depend partly on its design and manufacture. Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential.

Drug Bioavailability

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Scientist in Lab

CBD Bioavailability

What affects CBD bioavailability?

There are two main reasons why this happens. First, CBD is hydrophobic, meaning that it is not very water-soluble. In the same way that oil does not like to mix with vinegar, CBD does not like to stay in your bloodstream. Instead, it rapidly diffuses out of your blood and accumulates into your fatty tissues. Unfortunately, this significantly reduces the amount of bioactive CBD that can enter your systemic circulation, allowing for less CBD to be carried to its active sites in your body and thus lowering its overall bioavailability.

Second, when an organic compound like CBD enters your gut, it has to pass through the liver before it enters your circulation. During this transition, the liver will actively reduce the amount of CBD, either through absorption or through chemical breakdown by liver enzymes. This phenomenon is called the “first-pass effect,” where passing through the liver reduces the concentration of bioactive compounds.

‘Should I Be Vaping CBD?’: Why Vaporization Works Better Than Ingestion

Maximizing CBD Bioavailability Rates

Properly selecting your CBD consumption method can have a big impact on bioavailability. For example, orally consumed CBD will have a bioavailability of between 4% and 20%, while vaporized CBD can reach as high as 56%.

To maximize CBD bioavailability we recommend two methods of CBD consumption:

  • CBD Vapes
  • “Water-Soluble” CBD

Both methods are effective ways to deliver CBD fast and have the maximum levels of CBD penetrate your cells immediately. That being said, vapes and waters are not always the best CBD products for all conditions. For example, when treating skin conditions or spot treating pain, we still recommend CBD topicals.

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Man Vaping CBD

CBD Vape Bioavailability

Vaporized CBD consumption has been well documented and the numerous studies show bioavailability rates as high as 56%.

Vaporized consumption involves inhaling CBD directly into the lungs, typically through a vape pen or vaporizer device.

By directly entering the lungs, the CBD can then quickly and directly enter the bloodstream, with decreased breakdown rates and higher bioavailability.

With numerous medical studies reporting bioavailability rates between 34–46%, and some even reporting up to 56%, vaporizing CBD is by far one of the most effective methods to take CBD, and our recommended method.

What is CBD Bioavailability and Why Does it Matter?

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CBD Water In Bottle

“Water-Soluble” CBD Bioavailability

While a newer product, the International Cannabidiol Organization of Manufacturers and Research recently released a study with CBD Pur US showing that a “water-soluble” CBD product can increase bioavailability rates up to 46% depending upon a person’s metabolism.

As a market leader in the CBD topical space, TheraJoy has been proudly manufacturing our complete line of CBD products in the United States for three years. TheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed. Our product line is all-natural, organic, vegan, gluten-free and kosher.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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Dementia And Cannabidiol (CBD)

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Summary:

Nearly everyone has experienced losing their keys, forgetting a name, or walking into a room not remembering why at some point in their lifetime, now imagine that happening more frequently, combined with thoughts and behavior changes. For some this a harsh reality. Dementia is a group of conditions characterized by impairment of at least two brain functions, and it is life-altering. However, there may be new hope. CBD is gaining attention as a potential therapeutic treatment for both Alzheimer’s disease and vascular dementia, the two most common types of dementia.

In this article, we discuss dementia and it’s common causes, Alzheimer’s disease, treating Alzheimer’s disease with CBD, vascular dementia, and treating vascular dementia with CBD.

Dementia And Cannabidiol (CBD)

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Wheelchair Patient with Doctor

Similar to arthritis and heart disease, dementia is not a specific disease, but rather a group of conditions characterized by the impairment of at least two brain functions, such as memory loss and judgment.

Common symptoms of dementia include forgetfulness, limited social skills, and thinking abilities so impaired that it interferes with daily functioning.

Dementia

What is dementia?

Cognitive decline is easily one of the biggest fears among people over the age of 50. Nearly everyone has experienced losing their keys, forgetting a name, or walking into a room not remembering why at some point in their lifetime.

But imagine that happening more frequently, combined with thoughts and behaviour changes. The fear of developing a form of dementia, such as Alzheimer’s disease, is real for so many people. That same fear is the reason that learning more about the disease, including prevention and new Alzheimer’s treatments is very important to living the most fulfilled and healthy existence possible.

What are the effects of cannabis oil and Alzheimer’s disease?

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Brain Concept

Common Causes Of Dementia

The two most common causes of dementia are Alzheimer’s disease and vascular dementia.

Dementia is not a specific disease. It’s an overall term that describes a group of symptoms associated with a decline in memory or other thinking skills severe enough to reduce a person’s ability to perform everyday activities. Alzheimer’s disease accounts for 60 to 80 percent of cases. Vascular dementia, which occurs after a stroke, is the second most common dementia type. But there are many other conditions that can cause symptoms of dementia, including some that are reversible, such as thyroid problems and vitamin deficiencies.

What Is Dementia?

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Senior Male

Alzheimer’s Disease

Considering as many as 5.5 million Americans have Alzheimer’s disease, chances are, your life has already been touched by the disease in one way or another.

Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills, and eventually the ability to carry out the simplest tasks. In most people with Alzheimer’s, symptoms first appear in their mid-60s. Estimates vary, but experts suggest that more than 5.5 million Americans may have Alzheimer’s.

Alzheimer’s Disease Fact Sheet

Alzheimer’s Disease Statistics

The following statistics come from the Alzheimer’s Association of America.

  • 6th leading cause of death in the United States, but recent estimates indicate that the disorder may rank 3rd, just behind heart disease and cancer
  • 5.7 million Americans are living with Alzheimer’s, this is projected to grow to 14 million by 2050
  • 16.1 million Americans provide unpaid care for people with Alzheimer’s disease or other dementia
  • 18.4 billion hours of care valued at over $323 billion dollars is provided
  • 1 in 3 seniors die with Alzheimer’s or another dementia
  • 66% of Americans with Alzheimer’s are women
  • $7.9 trillion could be saved in medical and care costs with an early and accurate diagnosis of the condition
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Medical Technician

Treating Alzheimer’s Disease With CBD

Neurodegenerative diseases, such as Parkinson’s, Multiple Sclerosis, and Alzheimer’s, often involve inflammation of the neural tissue. The initial inflammation that occurs is thought to be acting as a defence mechanism in the earlier stages. But after a while, it could develop into uncontrolled chain reactions, leading to chronic neuronal deterioration and inflammation. So, utilizing cannabis oil as an anti-inflammatory could help slow down the progression of the disease, allowing patients the option of an alternative, new Alzheimer’s medicine.

The release of reactive oxygen and oxidative stress are both key components of Alzheimer’s disease and tied to immune inflammation. Oxidative stress is generated when inflammation happens. This decreases the antioxidant ability of cells, causing free radicals production and reaction with proteins and fatty acids within cell membranes. When the amyloid beta is present, there is an elevation of reactive oxygen species in adjoining cells through exchanges with the membranes. This results in a loss of neurons and synapses within the brain, resulting in memory loss and a variety of other neurological symptoms. An antioxidant would help to slow it down.

Cannabis oil is getting attention for potentially aiding in the neurogenesis process (new neural tissue). With Alzheimer’s disease, neural tissue is on a course of rapid destruction, leading to the debilitating neurological effects such as memory loss, cognitive loss, and severe changes in personality. In fact, people who were once thought of as loving, kind, and gentle, can become mean and selfish, something loved ones have difficulty understanding. And, one of cannabis oil medical benefits is thought to be slowing down the progression of these devastating effects, if it stimulates neural tissue.

What are the effects of cannabis oil and Alzheimer’s disease?

Vascular Dementia

Vascular disease occurs where blood vessels are damaged and the supply of oxygen is at risk. If oxygen supply fails in the brain, brain cells are likely to die leading to a series of mini strokes (infarcts) and possible vascular dementia. Vascular dementia accounts for 20%-30% of all cases of dementia.

The mini strokes that cause vascular dementia are often so slight that they cause no immediate symptoms, or they may cause some temporary confusion. However, each stroke destroys a small area of cells in the brain by cutting off its blood supply and the cumulative effect of a number of mini strokes is often sufficient to cause vascular dementia. Vascular dementia and Alzheimer’s disease frequently occur together and they may often act in combination to cause dementia.

Vascular dementia

Treating Vascular Dementia With CBD

While the research is still in its infancy, there is promising data from the US National Institute of Health (NIH).

Vascular dementia is a general term describing problems with reasoning, planning, judgment, memory and other thought processes caused by brain damage from impaired blood flow to one’s brain. To effectively treat vascular dementia, a 2016 study by the US National Institute of Health (NIH) found that activating CB2 (cannabinoid) receptors in the brain helped recover better blood flow to the brain. Activating the CB2 receptors with CBD has increased brain cell activity and helped reduce brain cell damage commonly associated with vascular dementia.

Using CBD (Cannabidiol) to Treat the Symptoms of Alzheimer’s & Other Dementias

Considering there is interesting clinical evidence showing that CBD may be able to target the underlying processes behind dementia, particularly Alzheimer’s disease, why wouldn’t you try it?

At TheraJoy, we have been making CBD products in the US for three years, and are proudly a market leader in topical CBDTheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed. Our product is all-natural, organic, vegan, gluten-free and kosher.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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Making Hydrophobic Cannabidiol (CBD) Water Soluble

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Summary:

Cannabinoids like CBD and THC are hydrophobic, which means they are oily and tend to repel water or fail to mix with it. With the help of a little science, we can make CBD form that is nearly water-soluble. CBD water is made using a process where sound waves break up CBD clusters into micro-sized particles that are smaller than 100 nanometers. The nano-sized nutrients available in CBD water soar past the blood-brain barrier and penetrate cells immediately, allowing for nearly 100% bioavailability and absorption.

In this article, we discuss CBD, what is water-soluble CBD and how to make it, types of water-soluble CBD and how they are different, the benefits of water-soluble CBD, and the bioavailability of CBD water.

Making Hydrophobic Cannabidiol (CBD) Water Soluble

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Clear Liquids

Cannabinoids like CBD and THC are hydrophobic, which means they are oily and tend to repel water or fail to mix with it. However, with the help of a little science, they can be formulated into water-compatible nanoemulsions. In this form, they appear water-soluble.

What Is CBD?

CBD, or cannabidiol, is one of many cannabinoids. While many plants contain cannabinoids, most people associate them with cannabis or hemp.

Unlike the more notorious cannabinoid THC or tetrahydrocannabinol, CBD does not produce a euphoric “high” or psychoactive effect. This is because CBD does not affect the same receptors as THC.

The reasons people have for consuming CBD vary, from chronic pain and inflammation to nausea-related symptoms of chemotherapy to general overall wellness. CBD is known to work as a powerful pain-reliever and anti-inflammatory, and the benefit is that there are no psychoactive effects and it is made of safe and non-addictive plant materials. The effects that CBD will have on you will depend on many factors including your experience with cannabis and CBD, your tolerance level, your current ailments and condition, your endocannabinoid levels, and other factors. All of this will not only affect how CBD interacts with your body and the effects you will feel, but also whether or not it is worth it for you to take as a supplement.

CBD Water

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Water with Bubbles

What Is “Water-soluble CBD”?

The term “water-soluble CBD” has lately been used extensively in the medical cannabis industry. “Water-soluble” means able to homogeneously incorporate into water by separating into molecules or ions (dissolve like sugar, alcohol or salt). Oily substances, however, are repelled by water, which forces them to stay separate from it.

CBD, THC and other oils can, however, be made water-compatible if they are formulated as oil-in-water nanoemulsions, which are stable and visually homogeneous oil/water mixtures. Nanoemulsions can be prepared in concentrated forms (tens of mg/ml) that are fully miscible with water and, therefore, appear water-soluble. In addition, nanoemulsions can be made translucent and practically tasteless, which means that they can be mixed into water without compromising its optical clarity or taste.

Can CBD or THC be Made Water-Soluble?

Making Water-soluble CBD

CBD water is made using a process called nanotechnology, which uses soundwaves to break up CBD clusters into micro-sized particles that are smaller than 100 nanometers. The result is a “water compatible” product that is small enough to dissolve and blend with water molecules, allowing for immediate bioavailability that many brands call the “nano-amplified effect.”

While other CBD products that have to reach the digestive system before taking effect, the nano-sized nutrients available in CBD water soar past the blood-brain barrier and penetrate cells immediately, allowing for nearly 100% bioavailability and absorption. These immediate, CBD-filled effects are why so many people enjoy drinking CBD water over other CBD edibles, although there are benefits to all of it depending on what you’re looking to achieve.

CBD Water

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Fit Woman Drinking Water

Types of Water-soluble CBD

  • Liposomes
  • Microemulsions
  • Nanoemulsions

How Are They Different?

Macroemulsions are common emulsions with droplets averaging over 1 micron in diameter and generally having wide droplet size distributions. They are unstable and tend to separate into an oil layer at the top and a water layer at the bottom, sometimes with a mixed layer in between. Due to their lack of stability, macroemulsions are generally not suitable as water-compatible cannabinoid delivery vehicles.

Microemulsions are translucent and thermodynamically stable mixtures of oil, water and surfactants having average droplet diameters below 100 nm. They can be spontaneously formed by “solubilizing” the oil in water or a beverage by very high amounts of surfactants – substantially higher than the amount of the oil. Because of many undesirable side-effects caused by concentrated surfactants (health issues, taste deterioration, etc.), the use of microemulsion-based, water-compatible cannabis oil formulations is disadvantageous. Furthermore, it is frequently impossible to achieve the desired cannabinoid concentration in a beverage without exceeding maximum permitted surfactant levels.

Liposomes are spherical structures with diameters from about 50 to 5000 nm formed by one or more concentric phospholipid bilayers with an aqueous phase inside and in-between the bilayers. Liposomes can entrap water-soluble (hydrophilic) active ingredients in their internal water compartment and water-insoluble (hydrophobic) active ingredients in their bilayer membrane. The latter property makes it possible to use liposomes to formulate water-compatible cannabis extracts. This, however, involves complex preparation procedures and, as with microemulsions, very high surfactant (lecithin phospholipids) concentrations. In addition, it is difficult to produce liposomal formulations using natural cannabis extracts, requiring the use of synthetic or isolated cannabinoids instead.

Water-Soluble Cannabis Oils: Microemulsion, Liposomes or Nanoemulsion?

Benefits Of Water-soluble CBD

  • Easy to Mix
  • Increased Bioavailability
  • Less Waste
  • Quick Onset
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Scientists Working

CBD Water Bioavailability

Bioavailability is defined as: “the amount of a substance that enters the bloodstream when introduced into the body and so is able to have an active effect.”

Since our bodies are made of ~60% water, CBD naturally resists absorption into the bloodstream. This has a big impact on the bioavailability of some of the most popular and convenient forms of taking CBD including capsules, tinctures, topicals, edibles, and drinks. As an example, when oil-based CBD capsules or soft gels are swallowed, some studies show that as little as 4% of the substance actually makes it to the bloodstream. What this means is that up to 96% of the CBD ends up being flushed from the body without ever having an active effect.

Water Soluble CBD Explained

CBD is relatively new, which means there are still limited studies available to support the benefits it provides, and there are even fewer studies about the effects of CBD water. As a potential user, you will need to work out the ideal dosage for your condition, just remember “low-and-slow” – start with a low dosage, and slowly work your way up.

Most CBD water products contain between 5mg and 20mg of CBD, and they are made to consume in a single serving like any other water beverage so you don’t have to ration it for appropriate dosing.

At TheraJoy, we always the finest all-natural ingredients in our line of topical CBD products. We offer purity you can trust, guaranteed, and we are always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. If you use CBD and want an organic, vegan, gluten-free, and kosher product, then you need TheraJoy. Make it part of your daily regime to maximize the benefits.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

 

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Understanding CBD Drug Interactions

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Summary:

Whenever multiple drugs are taken, there is a chance an interaction among the drugs will occur. Virtually all chemical compounds, from over-the-counter drugs and prescription pharmaceuticals to illicit substances, interact with other compounds. Drug interactions are complex and often unpredictable. A known interaction may not occur in every individual. While CBD produces very few side-effects and is considered to be generally safe for use, there are some risks that should be properly understood by all CBD users.

In this article, we discuss drug interactions, predicting drug interactions, additive vs. synergistic interactions, CBD drug interactions, the cytochrome P450 enzyme system, documented CBD drug interactions, and the grapefruit test.

Understanding CBD Drug Interactions

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Woman Holding Prescription Pill

Whenever multiple drugs are taken, there is a chance an interaction among the drugs will occur. The chemical interactions may increase or decrease the effectiveness of the drugs or their side effects, and the chances of drug interactions increase with the number of drugs being taken.

Drug Interactions

Whenever you consume a chemical compound, you must consider the possible interactions. Even innocuous and common chemicals like caffeine have interactions, some of which can be severe. Similarly, cannabidiol, while well tolerated by most users, has some interactions.

Virtually all chemical compounds, from over-the-counter drugs and prescription pharmaceuticals to illicit substances, interact with other compounds. There are, for example, 82 identified drug interactions with caffeine (of which 25 are classified as moderately severe to severe). Even seemingly benign substances, like grapefruit, are known to interact with many prescription drugs.

How Does Cannabis Interact With Other Drugs?

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Senior and Adult Daughter

Can Drug Interactions Be Predicted?

Drug interactions are complex and often unpredictable. A known interaction may not occur in every individual. This can be explained because there are several factors that affect the likelihood that a known interaction will occur. These factors include differences among individuals in their:

  • genes,
  • physiology,
  • age,
  • lifestyle (diet, exercise),
  • hydration,
  • underlying diseases,
  • drug doses,
  • the duration of combined therapy, and
  • the relative time of administration of the two substances. (Sometimes, interactions can be avoided if two drugs are taken at different times.)

Drug Interactions

Additive Vs. Synergistic

Before discussing CBD drug interactions further, it’s important to understand interactions in terms of medicine and pharmacology. There are two types of interactions – additive and synergistic.

Additive simply means the interaction between two chemicals equals the sum of their parts (e.g. 1+1 = 2). Synergistic means that when two chemicals interact, the effect is greater than the sum of their parts (e.g. 1+1 = 3. Sounds like “alternative math!”).

How Does Cannabis Interact With Other Drugs?

CBD Drug Interactions

While CBD produces very few side-effects and is considered to be generally safe for use, there are some risks that should be properly understood by all CBD users.

Research has begun to demonstrate that cannabidiol (CBD) has the potential to effectively help a large number of people. CBD interacts with the endocannabinoid system in a way that produces very few unintended side-effects.

While the majority of the vast majority of the science indicates CBD is safe for use and consumption, it does pose a few risks that, if not properly understood, could be dangerous.

Drugs that May Interact with CBD Oil

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Scientist With Notepad

Cytochrome P450 Enzyme System

Part of your liver, the cytochrome P450 enzyme system is responsible for metabolizes any potentially toxic compounds you ingest, including over 60% percent of any drugs you have ever consumed.

CBD can inhibit the cytochrome P450 system’s ability to metabolize certain drugs, leading to an overall increase in processing times.

One of these risks is the inhibition of the cytochrome P450 enzyme system.

According to Davis’s Drug Guide, this system contains more than 50 enzymes that process and eliminate toxins.

Drugs that May Interact with CBD Oil

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Assortment of Pills

Documented CBD Drug Interactions

What drugs should you be concerned about? Due to the fact that the cytochrome P450 is well-documented, there is a list of known interactions.

Any drug metabolized by CYP450 enzymes could potentially interact with cannabidiol. According to the Indiana University Department of Medicine, drugs known to use the CYP450 system include:

  • Anesthetics
  • Angiotensin II Blockers
  • Anti-epileptics
  • Antiarrhythmics
  • Antibiotics
  • Antidepressants
  • Antihistamines
  • Antipsychotics
  • Benzodiazepines
  • Beta-blockers
  • Calcium Channel Blockers
  • HIV Antivirals
  • HMG CoA Reductase Inhibitors
  • Immune Modulators
  • NSAIDs
  • Oral Hypoglycemic Agents
  • PPIs
  • Prokinetics
  • Steroids
  • Sulfonylureas

This list does not include all of the potential medications impacted by cannabidiol. Nor will every medication in the categories contained on this list will cause an interaction. For these reasons, you should consult with a medical professional before supplementing with CBD.

Drugs that May Interact with CBD Oil

Another potential interaction could come in the form of prodrugs. A prodrug is compound that, on administration, must undergo chemical conversion by metabolic processes before becoming an active pharmacological agent; a precursor of a drug.

Grapefruit, Credit: Stock Photography
Grapefruit

The Grapefruit Test

If you are taking another medication not found on the list above, and are still concerned about a possible interaction with CBD, then we recommend the grapefruit test.

Have you ever been told not to take your medication with grapefruit? This is because compounds in grapefruits can interfere with the metabolism of many medications.

CBD does the same thing. But as I said above, the effect is even stronger with CBD.

Do the grapefruit test with your doctor or pharmacist. Ask them: “Should I avoid eating grapefruits or drinking grapefruit juice with this medication?”

They will know exactly what you are talking about. If they say yes, you should avoid grapefruits with your medication, you now know you need to be careful about mixing CBD with those same meds as well. Talk to your doctor about CBD and tell them about it if they say you should avoid grapefruits with your medication.

CBD and Drug Interactions: An Easy Guide

At TheraJoy, we are proudly a market leader in topical CBD products. TheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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Quitting Smoking With Cannabidiol (CBD)

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Summary:

In a double-blind, placebo-controlled study, CBD reduced the consumption of cigarettes by tobacco users by 40%. While the research is still limited and new, it is promising. In this article, we discuss nicotine use in the United States, nicotine dependence, the symptoms of nicotine use and withdrawal, and quitting smoking with CBD.

In this article, we discuss nicotine use in the United State, nicotine dependence, the negative effects of nicotine use, and quitting smoking with cannabidiol.

Quitting Smoking With Cannabidiol (CBD)

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Woman Smoking Cigarette

Some early research has suggested that inhaling cannabidiol with an inhaler for one week might reduce the number of cigarettes smoked by about 40% when compared to baseline. Even the National Institutes of Health has stated: “The role of the endocannabinoid system in nicotine addiction is being increasingly acknowledged.”

Nicotine Use In The United States

While cigarette smoking is down in the United States, it’s still a major issue for our nation.

According to a 2015 report put out by the National Institute on Drug Abuse, a division of the National Institutes of Health, nicotine is often as addictive as heroin and cocaine. Nicotine stimulates the release of dopamine, a powerful neurotransmitter, in the pleasure circuits of the brain. Once a person is addicted to nicotine, their brain continually craves the nicotine so more dopamine will be released and give them those intense pleasurable sensations again.

The report goes on to say that about thirty-five million people know that smoking is bad for their health and want to break their nicotine habit. However, more than eighty-five percent of those who try to stop using tobacco products end up having a relapse, often within the first week when the withdrawal symptoms are the most severe.

Can CBD Help Break The Nicotine Habit

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Cigarette and Ashtray

Nicotine Dependence

Dependence is defined as “being abnormally tolerant to and dependent on something that is psychologically or physically habit-forming (especially alcohol or narcotic drugs)”.

For some people, using any amount of tobacco can quickly lead to nicotine dependence. Signs that you may be addicted include:

  • You can’t stop smoking. You’ve made one or more serious, but unsuccessful, attempts to stop.
  • You experience withdrawal symptoms when you try to stop. Your attempts at stopping have caused physical and mood-related symptoms, such as strong cravings, anxiety, irritability, restlessness, difficulty concentrating, depressed mood, frustration, anger, increased hunger, insomnia, constipation or diarrhea.
  • You keep smoking despite health problems. Even though you’ve developed health problems with your lungs or your heart, you haven’t been able to stop.
  • You give up social or recreational activities in order to smoke. You may stop going to smoke-free restaurants or stop socializing with certain family members or friends because you can’t smoke in these locations or situations.

Nicotine dependence

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Doctor Reviewing Lung X-ray

Negative Health Effects Of Nicotine Dependence

The negative health effects include:

  • Lung cancer and other lung diseases. Smoking causes nearly 9 out of 10 lung cancer cases. In addition, smoking causes other lung diseases, such as emphysema and chronic bronchitis. Smoking also makes asthma worse.
  • Other cancers. Smoking is a major cause of cancers of the esophagus, larynx, throat (pharynx) and mouth and is related to cancers of the bladder, pancreas, kidney and cervix, and some leukemias. Overall, smoking causes 30 percent of all cancer deaths.
  • Heart and circulatory system problems. Smoking increases your risk of dying of heart and blood vessel (cardiovascular) disease, including heart attack and stroke. Even smoking just one to four cigarettes daily increases your risk of heart disease. If you have heart or blood vessel disease, such as heart failure, smoking worsens your condition. However, stopping smoking reduces your risk of having a heart attack by 50 percent in the first year.
  • Diabetes. Smoking increases insulin resistance, which can set the stage for the development of type 2 diabetes. If you have diabetes, smoking can speed the progress of complications, such as kidney disease and eye problems.
  • Eye problems. Smoking can increase your risk of serious eye problems such as cataracts and loss of eyesight from macular degeneration.
  • Infertility and impotence. Smoking increases the risk of reduced fertility in women and the risk of impotence in men.
  • Pregnancy and newborn complications. Mothers who smoke while pregnant face a higher risk of miscarriage, preterm delivery, lower birth weight and sudden infant death syndrome (SIDS) in their newborns.
  • Cold, flu and other illnesses. Smokers are more prone to respiratory infections, such as colds, flu and bronchitis.
  • Weakened senses. Smoking deadens your senses of taste and smell, so food isn’t as appetizing.
  • Teeth and gum disease. Smoking is associated with an increased risk of developing inflammation of the gum (gingivitis) and a serious gum infection that can destroy the support system for teeth (periodontitis).
  • Physical appearance. The chemicals in tobacco smoke can change the structure of your skin, causing premature aging and wrinkles. Smoking also yellows your teeth, fingers and fingernails.
  • Risks to your family. Nonsmoking spouses and partners of smokers have a higher risk of lung cancer and heart disease compared with people who don’t live with a smoker. If you smoke, your children will be more prone to SIDS, worsening asthma, ear infections and colds.

Nicotine dependence

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Vape and Cigarette

Quitting Smoking With Cannabidiol

For cigarette smokers, CBD has shown promise in a double-blind, placebo-controlled study.

A study shows that CBD reduces the consumption of cigarettes by tobacco users by 40%. In a double blind, placebo controlled study, 24 cigarette smokers were recruited and split into two groups. One group was given inhalers containing CBD oil and the other were given a placebo. Both groups were told to use the inhalers whenever they felt the urge to smoke during a one week period.

The researchers found that over the treatment week those who used the placebo showed no change in the number of cigarettes they smoked. In contrast, the ones treated with CBD saw a significant reduction of cigarettes smoked by 40% during the treatment. Moreover, participants who used CBD did not report experiencing increased cravings for nicotine during the study’s duration. This preliminary data suggest CBD to be a potential treatment for nicotine addiction that warrants further exploration.

CBD Reduces Cigarette Smoking By 40% – Study

This is exciting research for anyone who has been battling nicotine addiction. If you’d like to quit, then you should try cannabidiol.

At TheraJoy, we always use pure organic coconut oil in TheraJoy Organic CBD Salve. We offer purity you can trust, guaranteed, and we are always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. If you use CBD and want an organic, vegan, gluten-free, and kosher product, then you need TheraJoy. Make it part of your daily regime to maximize the benefits.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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CBD Buying 101: Safely Purchasing Cannabidiol 

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Summary:

As the cannabis compound cannabidiol (CBD) gains more and more recognition for its potential therapeutic benefits, it seems as if it can be found everywhere and in everything. With so many choices available, many potential users are asking “How can I safely purchase CBD?

In this article, we discuss what is CBD, is CBD legal, things to know before purchasing CBD, key CBD buying criteria, CBD dangers, and where to buy CBD.

CBD Buying 101: Safely Purchasing Cannabidiol

Safety Concept, Credit: Stock Photography
Safety Concept

As the cannabis compound cannabidiol (CBD) gains more and more recognition for its potential therapeutic benefits, it seems as if it can be found everywhere and in everything; you can find it in everything from creams to suppositories, and everywhere from your local convenience store to your health food store. With so many choices available, many potential users are asking “How can I safely purchase CBD?

What is CBD?

Cannabidiol, or CBD, is just one of numerous cannabinoids found in the hemp plant. In 2003, the United States Government recognized its value and patented it (Patent No. 6,630,507) for its neuroprotectant and antioxidant properties.

Cannabinoids can be characterized by their ability to act on the cannabinoid receptors found throughout the body. CBD and other cannabinoids can promote the body’s healthy regulation of the central nervous, immune, and endocannabinoid systems.

Question Concept, Credit: Stock Photography
Question Concept

Is CBD Legal?

Due to the fact that CBD and THC are both derived from the same plant, the legality of CBD can be somewhat confusing.

When CBD is derived from the hemp plant it is considered legal in most places, because of the low content of the psychoactive cannabis compound THC (0.2%). In most places globally THC is deemed illegal with a few exceptions. If you are thinking of buying CBD oil it would be wise to check the legality of the country you reside in before making your purchase, luckily for those that that live stateside CBD derived from hemp is legal in all 50 states. However, if you live in Australia, Brazil, Singapore or Dubai, you will have to have a valid prescription before you can even think about taking CBD even if its derived from hemp.

Therefore it is important to know the law in the country or state you reside in.

How to Buy High Quality CBD Oil Online?

While we always recommend reviewing local regulations, products like that use CBD isolate are 100% legal for purchase and use in the United States. TheraJoy is an example of a CBD product made using CBD isolate.

Man Shopping, Credit: Stock Photography
Man Shopping

10 Things To Know Before Purchasing CBD

  1. Where, and how, the source plant was grown?
  2. How much THC, if any, exists in the product?
  3. How much CBD, exists in the product?
  4. What is the CBD concentration in the product?
  5. How was the CBD extracted?
  6. Are false or misleading product claims being made?
  7. Do third-party lab tests exist?
  8. Where is the product made?
  9. Is contact information for the manufacturer readily available?
  10. Does the manufacturer have an established history?

If the information listed above isn’t readily available on the product packaging or website, then you should consider another product.

Whenever possible, we recommend you look for an all-natural, organic CBD product, made in the United States.

Key CBD Buying Criteria

  1. Immediacy of Effects
  2. Ease of Use
  3. Concentration

It’s important to select the best CBD format for your condition; the right format will work fast and be easy to use. For example, patients suffering from sports injuries or skin conditions will be best served by CBD topicals, and patients trying to manage insulin resistance will be best served by orally consumed CBD or vaporized CBD. The correct dosage is important as well, for example, in small doses CBD has been shown to increase alertness, while larger doses can be used to encourage sleep.

CBD Dangers

A study, published this week in JAMA, found that nearly 70% of all products sold online made from cannabidiol — an extract of the marijuana plant also known as CBD — contained either higher or lower concentrations of the drug than indicated on the label. That could potentially mean those CBD products are ineffective or even dangerous.

Some CBD products examined in the study also contained significant amounts of THC, the chemical compound in cannabis that makes people feel high. Pure CBD should not contain THC, which is one reason experts say it has potential as a medical treatment, and is not something that can be abused. The presence of THC is especially concerning because CBD is sometimes used by children with seizure disorders, says lead author Marcel Bonn-Miller, PhD, adjunct assistant professor of psychology in psychiatry at the University of Pennsylvania.

The Real Risk of Buying Medical Marijuana Online

What To Avoid

  • Avoid mislabeled products, like hemp seed oil
  • Avoid products that claim to cure everything, they won’t
  • Look for quality, not low prices

Where To Buy CBD

As CBD becomes more popular, its availability has grown greatly. Here are just a few of the places that CBD is available.

However, all CBD is not equal. Due to the potential dangers associated with purchasing an unknown product from an unknown vendor, we recommend identifying a trusted vendor, and once you are comfortable with a CBD product and its efficacy, sticking with it. For therapeutic CBD topicals, consider TheraJoy, a leader in CBD topicals with a three-year history.

At TheraJoy, we always use the finest quality ingredients in our line of CBD topical products. We use 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. TheraJoy offers purity you can trust, guaranteed. We are always organic, vegan, gluten-free, and kosher. To maximize the benefits of our products make them part of your daily regime.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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Pet Health: Cannabidiol (CBD) and Cats

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Summary:

In the United States, there are 86 million owned cats, and most people consider their pets to be a furry extension of their family. When the unexpected occurs they are willing to do whatever they can, and in some cases, this includes considering an alternative, all-natural treatment like CBD.

In this article, we discuss what CBD is, CBD and your cat, the anecdotal support for CBD use for your feline, and a clinical opinion on CBD for cats.

Pet Health: Cannabidiol (CBD) and Cats

Veterinarian With Cat, Credit: Stock Photography
Veterinarian with Cat

In the United States, there are 86 million owned cats, and on average, cat owners spend $160 per year in recurring medical costs, according to the ASPCA. However, these costs can skyrocket rapidly when the unexpected happens.

“Diagnostic procedures alone can cost between $1,000 and $2,000,” says Baton Rouge, La., veterinarian Carrie Schultz, whose business, Housepet Housevet, specializes in house calls. Schultz knows how jarring veterinary expenses can be — her own cat recently racked up $2,000 in bills after it spent a weekend in intensive care at a small-animal hospital.

How Much Should You Pay to Save a Pet?

Most people consider their pets to be a furry extension of their family. When the unanticipated occurs they are willing to do whatever they can, and in some cases, this includes considering an alternative, all-natural treatment like CBD.

CBD Oil, Credit: Stock Photography
CBD Oil

What is CBD?

CBD or cannabidiol is a chemical compound found in the cannabis sativa plant. CBD is just one of more than 400 compounds found in the plant and is a cannabinoid in high concentrations.

Cannabinoids actively bind to special receptors on your cells and are part of what is known as your endocannabinoid system. This is a huge network of cell receptor proteins that have a vast array of functions. Some receptors are found within your central nervous system, whereas others are found in other places, such as your reproductive organs, skin and digestive tract.

This system is responsible for controlling your mood, appetite, sleep, immune response, movement, sperm development, ovulation and cognition.

Cannabidiol (CBD)

Owner And Cat, Credit: Stock Photography
Owner And Cat

CBD And Your Cat

According to one study, “a staggering 93 percent of pet owners felt that their animals performed equally well or better on CBD compared to standard veterinary medication and treatment”.

Consider the following first-person experience:

Blogger Kiki gave a true, heart-rending account of her short journey with her sick cat, Zaphod, and CBD oil for cats.

Despite taking good care of Zaphod, Kiki found herself having to stuff her feline friend with pharmaceuticals to manage inflammation, organ functioning, and more. However, after a while, this was not enough, and she decided to give CBD oil a try.

Kiki said: “Having talked to other pet owners about this, it seems as if many of us are just looking for another tool to ease pain and suffering in our elderly or terminally ill companions. I know that was the case for me.”

Kiki added Zaphod’s CBD oil to his wet food according to the package recommendations. However, this proved a bit excessive for the fella. The CBD oil relaxed him too much, causing him to be wobbly on his feet, so Kiki divided the dose over two meals. This hit Zaphod’s sweet spot. The CBD oil relaxed his facial expression and allowed his owners to pet and pick him up.

CBD for Cats—Dosage & Potential Benefits

The Clinical Value Of CBD For Cats

However, while CBD has many therapeutic uses for humans, there is currently no clinical evidence to support its use for felines. 

Male Doctor, Credit: Stock Photography
Male Doctor

According to Dr. Gary Richter, while CBD isn’t toxic to your cat, it is hard to justify clinically.

Although there have been no scientific studies that specifically investigate the impact of cannabis on pets, Dr. Gary Richter, a holistic veterinarian and owner and medical director of Montclair Veterinary Hospital and Holistic Veterinary Care in Oakland, California, says that CBD oil is generally safe for cats. However, there can be some adverse effects to giving your cat CBD oil, including gastrointestinal upset and some sedation, both of which can be relieved by discontinuing the use of the oil.

“I think the bigger issue, from a medical perspective, is making sure that animals are dosed appropriately. This means that the CBD oil is having the affect you want it to have, and that you’re not accidentally overdosing,” he says.

Dr. Liza Guess, a clinical assistant professor at the Ohio State University Department of Veterinary Medicine in Columbus, Ohio, says that the lack of official, documented research into the affects of cannabis products for cats would make her hesitant to recommend them.

“I have heard that, in humans, marijuana products can be used for neuropathic pain, intractable seizures, anxiety, and appetite stimulation. I have plenty of medications in each of those categories [that are not cannabis] that have been safely used in cats for years that I am very comfortable using and understand well,” she says. “These medications have gone through rigorous studies and are approved by the FDA. Why would I want to use a poorly understood treatment that I can’t guarantee is safe or even effective?”

She adds that the FDA does not regulate the CBD products that are available on the market, so consumers can’t be sure that they’re giving their pets the dosage that they think they are.

“Pet owners looking to give their animals CBD oil should do their due diligence before purchasing anything online,” Richter says. “The marketplace is very much a ‘buyer beware’ environment, and people should be sure that the product they’re buying has been laboratory tested for both content, as well as contaminants like bacteria, fungus, and heavy metals.”

Also, it’s worth nothing that while CBD oil is typically quite safe for cats and dogs, cannabis plants are not. “There is plenty of documentation of marijuana toxicity in cats, for those that nibble on the plants,” Guess says.

CBD Oil for Cats: What You Need to Know

At TheraJoy, we have been making CBD topical products in the US for the past three years, and are proudly a market leader. TheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed. Our products are always all-natural, organic, vegan, gluten-free and kosher.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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CBD, Obesity, and Weight Loss

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Summary:

When over two-thirds of American adults are overweight and one-third consistently weigh-in as obese, it’s clear, the United States is in an “obesity epidemic”. Being overweight or obese can increase the risk of many health problems, such as diabetes, heart disease, and certain cancers. CBD, or cannabidiol, is the second most common cannabinoid found in the hemp or cannabis plant, and it may be just what we need as a nation to break free of this epidemic.

In this article, we discuss obesity, the health risks of obesity, the body mass index (BMI), CBD for weight loss, and CBD dosage for weight loss.

Cannabidiol (CBD), Obesity, and Weight Loss

Man Eats Fast Food, Credit: Stock Photography
Man Eats Fast Food

Our nation is fighting an obesity epidemic. Today, over 2/3 of American adults are overweight.

When over two-thirds of American adults are overweight and one-third consistently weigh-in as obese, this is no longer just a threat or stereotype. It’s an epidemic. Moreover, weight has heavily affected children of this nation as well. But what’s the big deal? Can’t everyone just diet and shed the excess weight? If it were that simple, no one would have weight-related health issues. Unfortunately, science still knows very little about treating obesity. However, recent research has shown the potential of an unlikely source… cannabidiol. But what are the real health implications of obesity and how can anything related to cannabis help with weight loss?

New Obesity Miracle Cure? Can CBD From Cannabis Be The Answer To Curing Obesity?

Woman Post Exercise, Credit: Stock Photography
Woman Post Exercise

Obesity

Obesity is a very common disorder with over 3 million cases in the US per year; it is defined as a having excessive body fat that increases the risk of health problems. A weight that is higher than what is considered as a healthy weight for a given height is described as overweight or obese. Body Mass Index, or BMI, is used as a screening tool for overweight or obesity.

The Health Risks Of Being Overweight

Being overweight or obese can increase the risk of many health problems, such as diabetes, heart disease, and certain cancers. Furthermore, if you are pregnant, excess weight may lead to short- and long-term health problems for you and your child.

Excess weight may increase the risk for many health problems, including:

  • Certain Types of Cancer
  • Fatty Liver Disease
  • Heart Disease and Strokes
  • High Blood Pressure
  • Kidney Disease
  • Osteoarthritis
  • Pregnancy problems, such as High Blood Sugar during Pregnancy, High Blood Pressure, and increased risk for Cesarean Delivery (C-section)
  • Sleep Apnea
  • Type 2 Diabetes

Health Risks of Being Overweight

Body Mass Index (BMI), Credit: Stock Photography
Body Mass Index (BMI)

Body Mass Index (BMI)

As mentioned above, the Body Mass Index, or BMI, is used as a screening tool for identifying people who are overweight or obese.

A good way to decide if your weight is healthy for your height is to figure out your body mass index (BMI). You and your health care provider can use your BMI to estimate how much body fat you have.

Your BMI estimates how much you should weigh based on your height.

There are many websites with calculators that give your BMI when you enter your weight and height.

You can also calculate it yourself:

  • Multiply your weight in pounds by 703.
  • Divide that answer by your height in inches.
  • Divide that answer by your height in inches again.

For example, a woman who weighs 270 pounds (122 kilograms) and is 68 inches (172 centimeters) tall has a BMI of 41.0.

Body mass index

What is CBD?

CBD, or cannabidiol, is the second most common cannabinoid found in the hemp or cannabis plant.

CBD is just one of the many active cannabinoids found in the cannabis plant and marijuana. Over the past few years, extensive research has been done on this ingredient, including all the amazing health benefits that it can bring. CBD has been proven to help fight cancer, reduce inflammation, relieve multiple sclerosis (MS) symptoms, reduce epileptic seizures, help with post-traumatic stress disorders, work as weight-loss supplements, improve blood sugar levels and blood pressure, and relieve chronic pain.

CBD Weight Loss: FAQs

Man On Scale, Credit: Stock Photography
Man On Scale

CBD For Weight Loss

How can CBD be used to maintain a healthy weight?

CBD And “Fat Browning”

CBD has the ability to induce “fat browning”.

In a newly published study in the scientific journal Molecular and Cellular Biochemistry, Korean researchers studied the effects of CBD administration on preadipocytes (immature fat cells) to explore potential benefits on the treatment and prevention of obesity. Remarkably, CBD was found to do the following:

Stimulate genes and proteins that enhance the breakdown and oxidation of fat
Increase the number and activity of mitochondria (which increases the body’s ability to burn calories)
Decrease the expression of proteins involved in lipogenesis (fat cell generation)

Collectively, these results stem from the ability of CBD to induce “fat browning” – that is, converting what is normally white-colored fat tissue (WAT-white adipose tissue) that stores energy to beige-colored fat tissue (BAT-brown and beige adipose tissue) that burns it. Previous studies have shown that boosting beige-colored fat in animals improves their glucose tolerance, making them more resistant to diabetes and various blood lipid abnormalities.

Can Cannabidiol (CBD) Help Support Weight Loss and Metabolism?

CBD Controls Blood Sugar Levels

CBD can aid in the prevention of obesity by controlling the appetite and maintaining the blood sugar levels.

The high blood sugar levels result in resistance to insulin, a condition where the cells do not respond to the primary hormone insulin which helps in the transportation of glucose.

The glucose is then utilized as a source of energy and does not respond to the signals of insulin.

It then leads to the development of diabetes resulting in a risk of developing weight loss and obesity issues.

CBD oil controls the blood sugar levels by the reduction of inflammation as it damages the insulin. It is because of the swelling that insulin resistance occurs.

CBD oil prevents such effects and improves the body’s metabolism related to sugar to aid in weight loss.

How To Lose Weight With CBD Oil? CBD Dosage For Weight Loss

Is There A Right Dosage?

The right CBD dosage differs for each person. Bodies are not all the same, and some require less CBD, while others require more.

There are some steps that can help you decide the right dose. First of all, you should consult a doctor, as he knows more information about this. You should start with a small dose of CBD to see if it works. Keep it like this for a while, and if you see no result, increase it. Remember that everything needs your patience, so don’t quit as soon as you think it’s not effective.

How Does CBD Support Weight Loss: All You Need to Know

CBD has shown great promise as an all-natural option for managing and maintaining a healthy weight. However, it’s important to remember that you should always maintain a “low and slow” strategy and avoid higher dosage levels which might result in inadvertent weight gain.

At TheraJoy, we are proudly a market leader in topical CBD productsTheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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CBD Effects On The Heart

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Summary:

Similar to arthritis, heart disease is an umbrella term that can describe a wide variety of conditions. CBD may be able to serve as a preventative medicine to curb the onset of cardiovascular disease and improve overall heart health. In this article, we discuss the relationship between cannabidiol and heart disease, scientific support for the impact CBD has on cardiovascular health, and other cardiovascular conditions supported by CBD.

CBD Effects On The Heart

Doctor Evaluates Female Patient, Credit: Stock Photography
Doctor Evaluates Female Patient

CBD, a compound found in the hemp plant, has been shown to mitigate cardiac dysfunction, increase blood flow, reduce scar tissue, reduce inflammation and it balances the death of cells that signal pathways in sugar-related diseases that affect the function of the heart.

What Is Heart Disease?

Similar to arthritis, heart disease is an umbrella term that can describe a wide variety of conditions.

Heart disease describes a range of conditions that affect your heart. Diseases under the heart disease umbrella include blood vessel diseases, such as coronary artery disease; heart rhythm problems (arrhythmias); and heart defects you’re born with (congenital heart defects), among others.

The term “heart disease” is often used interchangeably with the term “cardiovascular disease.” Cardiovascular disease generally refers to conditions that involve narrowed or blocked blood vessels that can lead to a heart attack, chest pain (angina) or stroke. Other heart conditions, such as those that affect your heart’s muscle, valves or rhythm, also are considered forms of heart disease.

Many forms of heart disease can be prevented or treated with healthy lifestyle choices.

Heart disease

Are You At Risk For Heart Disease?

The dangers of heart disease are real, but you can evaluate your risk.

There are risk factors that increase the potential to develop plaque within coronary arteries and cause them to narrow. Atherosclerosis (athero=fatty plaque + sclerosis=hardening) is the term that describes this condition. Factors that put people at increased risk for heart disease are:

  • Smoking
  • High blood pressure (hypertension)
  • High cholesterol
  • Diabetes
  • Family history of heart problems, especially heart attacks and strokes
  • Obesity

Since cardiovascular disease, peripheral artery disease, and stroke share the same risk factors, a patient who is diagnosed with one of the three has increased risk of having or developing the others.

Heart Disease (Cardiovascular Disease, CVD)

CBD Heart Disease Concept, Credit: Stock Photography
CBD Heart Disease Concept

Preventing Heart Disease

Healthy lifestyle choices can be key in preventing heart disease. Here are six steps you can take to reduce your chances of having heart disease.

  1. Avoiding excessive intake of alcohol
  2. Eating a diet that is low in salt, refined sugars, total fat, saturated fat, and cholesterol and high in fresh fruits and vegetables
  3. Exercising regularly (at least 150 minutes a week)
  4. Following instructions to ensure the safe use of medications and any OTC drugs
  5. Taking steps to reduce stress levels, or get help with stress management
  6. Quit smoking

CBD And Heart Disease

What is the relationship between CBD and heart disease?

Heart disease is the number one killer of both men and women in the US, causing approximately one-quarter of all deaths every year. CBD may be able to serve as a preventative medicine to curb the onset of cardiovascular disease and improve overall heart health.

For starters, CBD may help to the relax the arterial walls of the heart, which reduces tension in the blood vessels and can help reduce the work that the heart must do to pump blood. The cannabinoids also protect the heart against cardiomyopathy, which causes hardening and thickening of the arterial walls and limits blood flow.

CBD has also been shown to reduce plaque in the arterial walls, which makes it more difficult for the heart to pump blood properly. Studies have also shown that CBD is an effective agent against inflammation, which is linked to heart disease. CBD can stop the production of endotoxins, which are pro-inflammatory cytokines that can cause heart conditions to worsen.

The anti-inflammatory effects of CBD and its antioxidant effects can protect the heart against tissue damage.

Using CBD as a Preventative Medicine

Scientific Support For CBD And Heart Disease

CBD has been shown to impact three primary aspects of cardiovascular health. These include:

  • Reduction of arrhythmia
  • Reduction of heart inflammation
  • Lowering of blood pressure

Evidence is growing for all of these claims, as research has begun expanding concerning this important topic. One study in particular seems especially promising:

A study published in 2010 in the British Journal of Pharmacology, shows numerous promising results for those who desire a better understanding of the correlation and connection between CBD (cannabidiol) and overall cardiovascular health. Conducted upon groups of male Sprague-Dawley lab rats that were each administered two different doses of CBD, the animals were then observed and the results were carefully noted and analyzed.

Ultimately, the conclusion that the researchers on this project discovered, was that the application of CBD actually lowered the number of induced heart arrhythmias and infarct size, which is a scale used to determine heart failure and its correlation to death. In the end, these scientists were able to conclude that at least in this study, CBD was in fact cardioprotective, meaning that it was able to assist with the maintenance of cardiovascular health.

CBD Oil for Cardiovascular Health: Is It Practical?

Defibrillator, Credit: Stock Photography
Defibrillator

Other Cardiovascular Conditions Supported By CBD

Can CBD be used to treat other cardiovascular-related conditions?

Evidence suggests CBD may help in treating several other cardiovascular-related conditions, including:

  • Hypertension (high blood pressure)
  • Stroke
  • Cardiac arrest
  • Atherosclerosis
  • Cardiovascular disease

CBD Oil: A Positive Support for the Fight Against Heart Disease

At TheraJoy, we have been making CBD products in the US for three years, and are proudly a market leader in CBD topicalsTheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed. Our products are always all-natural, organic, vegan, gluten-free and kosher.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

Posted on

Managing Diabetes With Cannabidiol (CBD)

Diabetes Concept, Credit: Stock Photography

Summary:

Diabetes is a disease in which the body’s ability to produce or respond to the hormone insulin is impaired, resulting in abnormal metabolism of carbohydrates and elevated levels of glucose in the blood and urine. If you are someone you love is afflicted with diabetes, you aren’t alone. Over 100 million American adults — about 1/3 of the population — are currently living with either type 1 or type two 2, and another 84.1 million are pre-diabetic. Clearly, diabetes is a serious condition, but it is preventable. Can CBD be used to reduce the risk of diabetes?

Managing Diabetes With Cannabidiol (CBD)

Finger Tip Blood Testing, Credit: Stock Photography
Finger Tip Blood Testing

If you are someone you love is afflicted with diabetes, you aren’t alone. There are currently over 100 million cases of adult diabetes in America, this translates into roughly 33% of the population. With so many afflicted, researchers have been working on a cure for years, and now some researchers are looking to cannabidiol.

Over 100 million American adults — about 1/3 of the population — are currently living with either type one or type two diabetes.

Another 84.1 million are also prediabetic and, if they don’t take control of their condition, will end up with type 2 diabetes within about five years.

Clearly, the prevalence of diabetes in the United States is a serious problem. Doctors and researchers are working hard every day to try and solve it.

As a result of their hard work, they’ve found many possible solutions. One possible solution, in particular, has been getting a lot of attention lately — CBD oil and other CBD-infused products.

CBD And Diabetes: 5 Ways Cannabidiol May Help In Diabetes Management

Glucometer, Credit: Stock Photography
Glucometer

Diabetes

Diabetes is a disease in which the body’s ability to produce or respond to the hormone insulin is impaired, resulting in abnormal metabolism of carbohydrates and elevated levels of glucose in the blood and urine. This disease comes with a litany of symptoms and common complications.

Common Types Of Diabetes

  • Type 2 diabetes: A chronic condition that affects the way the body processes blood sugar (glucose).
  • Type 1 diabetes: A chronic condition in which the pancreas produces little or no insulin.
  • Pre-diabetes: A condition in which blood sugar is high, but not high enough to be type 2 diabetes.
  • Gestational diabetes: A form of high blood sugar affecting pregnant women.

Most people with the condition have type 2.

Diabetes Symptoms And Complications

The following are common symptoms of diabetes. However, for some with type 2 diabetes, the symptoms are so mild that they go unnoticed.

Common symptoms of diabetes:

  • Urinating often
  • Feeling very thirsty
  • Feeling very hungry – even though you are eating
  • Extreme fatigue
  • Blurry vision
  • Cuts/bruises that are slow to heal
  • Weight loss – even though you are eating more (type 1)
  • Tingling, pain, or numbness in the hands/feet (type 2)

Diabetes Symptoms

Insulin Injection, Credit: Stock Photography
Insulin Injection

Compounding the symptoms are a litany of common complications.

In addition, the following are common complications often stemming from diabetes:

  • Cardiovascular disease
  • Eye disease
  • Kidney disease
  • Nerve damage
  • Lower extremity ulcers and amputation
  • Complications during pregnancy
  • Oral disease
  • Mental illness

How Cannabis Oil Can Be Used For Diabetes Treatment And Prevention

Cannabinoids For Diabetes Sufferers

Recent research into the benefits of cannabinoids for diabetics has been

The 2005 research paper from the American Alliance for Medical Cannabis (AAMC) lists numerous benefits that both CBD and cannabis can have for diabetes sufferers including:

  • Stabilizing blood sugars
  • Arterial anti-inflammatory properties
  • “Neuroprotective” effects that help prevent inflammation of nerves and reduce the pain of neuropathy
  • “Anti-spasmodic agents” help relieve muscle cramps and the pain of gastrointestinal (GI) disorders
  • Acting as a “vasodilator” to help keep blood vessels open and improve circulation
  • Lowering blood pressure — which is vital for diabetics
  • Helping calm diabetic “restless leg syndrome” (RLS)

Cannabis Oil For Diabetes? The Positive Effects Of CBD On Insulin And Metabolism

Preventing Diabetes With CBD

Clearly, diabetes is a serious condition, but it is preventable. Can CBD be used to reduce the risk of diabetes?

Regular use of CBD oil products can have a positive effect on blood sugar levels as well as fasting insulin levels in the blood, which can reduce the onset of diabetes. Studies have shown that the use of CBD oil can not only lower fasting insulin levels, but also increase healthy cholesterol (HDL) and lower levels of insulin resistance, which can protect against the disease.

The ability for CBD oil to reduce the risk of diabetes also stems from its ability to help maintain a healthy body weight. Obesity is directly linked to the onset of diabetes, so controlling body weight is typically seen as an important preventative measure.

A high Body Mass Index (BMI), which is the total percentage of fat in the body, has been associated with an increased likelihood of developing diabetes. Studies have shown that regular CBD use can help to reduce the risk of obesity and lower BMI. Regular CBD users tend to have a lower BMI and a smaller waist circumference, both of which are risk factors for diabetes.

In fact, it has been estimated that obesity rates among cannabis users are approximately one-third lower compared to non-cannabis users. Other studies have shown that CBD can reduce the prevalence of diabetes in lab rats. Further, it has also been discovered that CBD can help the body convert white fat into fat-burning brown fat, which helps to stimulate the natural production of insulin and breakdown of sugar.

Using CBD as a Preventative Medicine

Stomach Fat, Credit: Stock Photography
Stomach Fat

Treating Insulin Resistance With CBD

A key factor in both pre-diabetes and type 2 diabetes, insulin resistance may be reduced by CBD.

Insulin resistance occurs when the body’s cells reject insulin, which is produced by the pancreas to regulate blood sugar. When the cells reject insulin, they cannot absorb glucose (sugar), which is needed for energy. This causes glucose to build up in the bloodstream and lead to high blood sugar levels.

Insulin resistance is a key factor in prediabetes and type 2 diabetes.

Researchers aren’t totally sure how CBD works to treat insulin resistance. But, many believe that credit belongs to CBD’s powerful anti-inflammatory benefits.

Many studies have a shown a connection between chronic inflammation and insulin resistance.

When inflammation is reduced, the immune system and cardiovascular system function better. A lack of inflammation can also improve cell growth and improve sugar metabolism.

If all of these systems throughout the body are working as efficiently as possible, the chances of developing insulin resistance and diabetes are decreased.

CBD And Diabetes: 5 Ways Cannabidiol May Help In Diabetes Management

Child Disinterested In Salad, Credit: Stock Photography
Child Disinterested In Salad

Preventing Obesity With CBD

CBD can do more than just help with insulin resistance, research also shows it can be effective in reducing obesity.

Several studies have been conducted to establish the effectiveness of CBD in reducing obesity. Recently, a study that was published by the American Journal of Medicine indicated that CBD users are less likely to suffer from metabolic disorder which is a common and major factor in obesity and other conditions like the heart disease and diabetes.

Researchers at the University of Miami studied the correlation between cannabis and metabolic syndromes like increased fat in the abdominal area, high blood pressure, increased blood sugar, and high cholesterol levels.

The study, which involved over 8,000 people at the age of 20-59 years, established that though 22% of the subjects are affected by metabolic syndrome, only less than 14% of CBD users suffer from the syndrome. It also established that people that have used cannabis or CBD in the past are less likely to suffer from this syndrome and 54% of CBD users are less likely to become obese.

Several studies have been conducted to establish the effectiveness of CBD in reducing obesity. Recently, a study that was published by the American Journal of Medicine indicated that CBD users are less likely to suffer from metabolic disorder which is a common and major factor in obesity and other conditions like the heart disease and diabetes.

Researchers at the University of Miami studied the correlation between cannabis and metabolic syndromes like increased fat in the abdominal area, high blood pressure, increased blood sugar, and high cholesterol levels.

The study, which involved over 8,000 people at the age of 20-59 years, established that though 22% of the subjects are affected by metabolic syndrome, only less than 14% of CBD users suffer from the syndrome. It also established that people that have used cannabis or CBD in the past are less likely to suffer from this syndrome and 54% of CBD users are less likely to become obese.

CBD and Obesity

Treating Diabetic Neuropathy With CBD

While not clinically validated, there has been speculation by some researchers and physicans that CBD may be useful in treating diabetic neuropathy.

To be clear, there has not to date been any clinical trials conducted on the effects of CBD oil for diabetic neuropathy. As such, any potential for CBD (or other cannabis compounds) to help treat the condition will have stemmed from speculative research that has been carried out mostly on animal models and/or cultured nerve cells.

That being said, the roles of CBD as a neuroprotectant and an analgesic (pain reliever) are very well known, and have been well-documented in recent years. In fact, the U.S. government actually holds a patent on the compound for its ability to protective nerve cells from damage and disease-induced degeneration.

As such, some researchers and physicians are speculating that a high-grade CBD oil may very well have the ability to protect nerve cells from diabetes-induced neuropathy, and perhaps even reverse damage that has already begun.

CBD Oil for Diabetic Neuropathy: What the Current Scientific Research Shows

Eye Health, Credit: Stock Photography
Eye Health

Treating Diabetic Retinopathy With CBD

Similar to with diabetic neuropathy, using CBD to treat diabetic retinopathy is speculative. However, there is some justification.

Up to 80% of diabetes patients that have had the disease for over a decade acquire a complication known as diabetic retinopathy (DRP), in which the cells of the retina are progressively damaged. This condition is responsible for approximately 12% of new cases of blindness each year in the USA.

DRP is associated with glucose-induced breakdown of the blood-retinal barrier, a network of tightly-packed cells that prevent unwanted substances in the blood from entering retinal tissue. This breakdown causes neural tissue to be exposed to neurotoxins, as well as increasing the chance of bleeding within the retina.

It is thought that the pro-inflammatory immune response and oxidative stress processes have a key role to play in the breakdown of retinal cells–and there is evidence that cannabidiol, with its known ability to combat both oxidative stress and inflammation, may be useful in treating the disorder. In a 2006 study published in the American Journal of Pathology, diabetic rats were administered with CBD and tested to determine the rate of retinal cell death. It was shown that treatment with CBD significantly reduced oxidative stress and neurotoxicity–including levels of tumor necrosis factor-a, a substance that is known to be involved in the inflammatory response–and protected against retinal cell death and the breakdown of the blood-retinal barrier.

Top 5 benefits of cannabis for diabetes

If you, or someone you love, is suffering from diabetes, consider cannabidiol. CBD is an all-natural treatment option with a growing body of scientific research documenting its therapeutic benefits for diabetics.

At TheraJoy, we have been making CBD products in the US for three years, and are proudly a market leader in topical CBDTheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed. Our product is all-natural, organic, vegan, gluten-free and kosher.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.